Targeting of Dicer-2 and RNA by a Viral RNA Silencing Suppressor in Drosophila Cells
نویسندگان
چکیده
منابع مشابه
Targeting of dicer-2 and RNA by a viral RNA silencing suppressor in Drosophila cells.
RNA interference (RNAi) is a eukaryotic gene-silencing mechanism that functions in antiviral immunity in diverse organisms. To combat RNAi-mediated immunity, viruses encode viral suppressors of RNA silencing (VSRs) that target RNA and protein components in the RNAi machinery. Although the endonuclease Dicer plays key roles in RNAi immunity, little is known about how VSRs target Dicer. Here, we ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2012
ISSN: 0022-538X
DOI: 10.1128/jvi.07229-11